021-51111890
购物车（）
sales@molnova.cn
Dimethyl malonate
CAS No. 108-59-8
Dimethyl malonate ( —— )
产品货号. M20375 CAS No. 108-59-8
丙二酸二甲酯是一种琥珀酸脱氢酶抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥340 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Dimethyl malonate
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述丙二酸二甲酯是一种琥珀酸脱氢酶抑制剂。
-
产品描述Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.
-
体外实验——
-
体内实验Animal Model:Sprague-Dawley male rats, cardiac arrest modelDosage:6 mg/kg/minAdministration:Intravenous infusion, 51 minResult:Improved ROSC after CA. Prevented the decline in neurological function and inhibited the apoptosis of hippocampal neurons at day 3 after CPR. Inhibited caspase-3 cleavage and increased HIF-1α expression at day 3 after CPR. Decreased the level of oxidative stress at day 3 after CPR. Inhibited excessive hyperpolarization of MMP and restrained the leakage of cytochrome C after 45 min reperfusion.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Succinate Dehydrogenase
-
研究领域——
-
适应症——
化学信息
-
CAS Number108-59-8
-
分子量132.11
-
分子式C5H8O4
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 100 mg/mL (756.94 mM)
-
SMILESCOC(=O)CC(=O)OC
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Xu J Pan H Xie X et .al.Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest[J].Neuroscience. 2018 Nov 21;393:24-32
产品手册
关联产品
-
Solvent Red 23
Solvent Red 23 是一种用于给非极性物质着色的溶剂染料。
-
Cyclo(L-Ala-L-Pro)
Cyclo(L-Ala-L-Pro) and cyclo(L-Val-L-Pro) inhibit aflatoxin production of Aspergillus parasiticus and Aspergillus flavus in liquid medium at concentrations of several hundred uM without affecting fungal growth.
-
Sulfo-SANPAH Crossli...
Sulfo-SANPAH 交联剂是一种水溶性同双功能蛋白质交联剂。
